Exposure to old formaldehyde compounds of liquid air freshener products on lung, heart and brain cell histology of mice (Mus musculus)

  • Delima Engga Maretha UIN Raden Fatah
    (ID)
  • Asnilawati Asnilawati
    (ID)
  • Vina Prisunarti Putri
    (ID)
  • Senja Senja
    (ID)
  • Tri Ayu
    (ID)
  • Muhammad Mustapha Adam
    (NG)
Kata Kunci: air freshener; alveolar histology; heart and brain; Mus musculus; environmental pollution

Abstrak

Air freshener is a product commonly used to reduce unpleasant odors. Air freshener contains compounds containing chemicals such as terpenes, aldehydes (formaldehyde), ethanol, phenol, linalool, citronellol, naphthalene, di-butyl phthalate (DBP), di-isobutyl phthalate (DIBP), di-isohexyl phthalate (DIHP) and 1,4 dichlorobenzenes (benzene). The purpose of this study was to determine the effect of exposure to liquid air freshener on the histology of alveolus, heart muscle, and brain in mice (Mus musculus). The design of this research is to use a post-test-only control group design. The post-test was done by observing the histology of the alveoli, heart muscle, and brain. After exposure to air freshener liquid as much as 3 ml 3 times a day for 6 weeks. The research subjects were 20 mice that were 2 months old. The data were tested using One Way ANOVA statistical test followed by Post Hoc Tukey. The results showed that air freshener had an effect on the alveoli (alveolar septum), the heart in the form of thinning of the heart muscle and there was a change in the thickness of the brain layer. Based on the research, it can be concluded that liquid air freshener affects the histology of the alveoli, heart muscle, and brain of mice. Therefore, the use of air fresheners should not be used in the long term.

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2022-06-30
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